Medication indicated in case of fever and pain of mild to moderate intensity.
Acetylsalicylic acid is, like all NSAIDs, a non-specific inhibitor of the enzyme cyclooxygenase (COX). It irreversibly acetylates this enzyme.
COXs are key enzymes of the arachidonic acid cascade, by which arachidonic acid, a lipid present in cell membranes, is transformed into prostanoid mediators. There are two types, COX-1, present in almost all tissues; and COX-2 induced locally by cytokines produced by leukocytes in response to microbial damage or invasion. COX-2 plays an important role in generating inflammation.
It produces pro-inflammatory prostanoid mediators, such as some prostaglandins and leukotrienes.
Inhibition of these enzymes by acetylsalicylic acid constitutes the main mechanism of its effects. COX-1 inhibition is responsible for many unwanted effects.
It is for: Analgesic and antipyretic / antiplatelet agent.
Active substance: Acetylsalicylic acid (500 mg).
Excipients and other constituents: Powdered cellulose, corn starch.
Store at room temperature, protected from light and moisture.
Do not take if you are allergic to any of the drug's constituents (active substances or excipients) or to other salicylates or non-steroidal anti-inflammatory drugs.
Keep out of the reach and sight of children.
You should not take it for more than 3 consecutive days, unless your doctor tells you to.
Use is not recommended if you have, or have ever had, gout, severe heart, liver (liver) or kidney problems.
Use is not recommended if you have, or have had, gastrointestinal problems (ulcers, gastritis, recurrent gastrointestinal bleeding, inflammatory bowel diseases - Ulcerative colitis and Crohn's disease)
Use is not recommended if you have, or have had, clotting problems, as it can increase the risk of bleeding, especially in the stomach. Check with your doctor or pharmacist.
Do not take this medicine if you are taking other non-steroidal anti-inflammatory drugs, sulfonylureas or antacids.
Do not take this medicine if you are taking oral anticoagulants or methotrexate.
During treatment, avoid drinking alcoholic beverages.
Pregnancy and breastfeeding:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
How to use:
Dissolve the tablet in a glass of water.
The cup must be made of glass or plastic and never made of metal or any other material.
Wait for the tablet to dissolve completely and take it immediately.
Take preferably at night, as recommended by a doctor or pharmacist.